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Prediction of a Therapeutic Dose for Buagafuran, a Potent Anxiolytic Agent by Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling Starting from Pharmacokinetics in Rats and Human

机译：通过基于生理学的药代动力学/药效学模型从大鼠和人体的药代动力学开始预测Buagafuran（一种有效的抗焦虑剂）的治疗剂量

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Fen Yang; Baolian Wang; Zhihao Liu; Xuejun Xia; Weijun Wang; Dali Yin; Li Sheng; Yan Li;
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1. Prediction of a Therapeutic Dose for Buagafuran, a Potent Anxiolytic Agent by Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling Starting from Pharmacokinetics in Rats and Human [J] . Fen Yang, Baolian Wang, Zhihao Liu, Frontiers in Pharmacology . 2017,第4期

机译：从大鼠和人体内的药代动力学出发，通过基于生理学的药代动力学/药效学模型预测布加呋喃（一种有效的抗焦虑药）的治疗剂量
2. Prediction of a potentially effective dose in humans for BAY 60-5521, a potent inhibitor of cholesteryl ester transfer protein (CETP) by allometric species scaling and combined pharmacodynamic and physiologically-based pharmacokinetic modelling [J] . WeberO., WillmannS., BischoffH., British Journal of Clinical Pharmacology . 2012,第2期

机译：通过异形物种缩放以及结合药效学和生理学的药代动力学模型预测BAY 60-5521（胆甾醇酯转移蛋白（CETP）的有效抑制剂）对人体的潜在有效剂量
3. Prediction of a potentially effective dose in humans for BAY 60-5521, a potent inhibitor of cholesteryl ester transfer protein (CETP) by allometric species scaling and combined pharmacodynamic and physiologically-based pharmacokinetic modelling [J] . WeberO., WillmannS., BischoffH., British Journal of Clinical Pharmacology . 2012,第2期

机译：通过异形物种缩放以及结合药效学和生理学的药代动力学模型预测BAY 60-5521（胆甾醇酯转移蛋白（CETP）的有效抑制剂）对人体的潜在有效剂量
4. Use of Cytochrome P450-Specific Parameters and Human Biomarker Data To Develop a Human Physiologically Based Pharmacokinetic/Pharmacodynamic Model for Dermal Chlorpyrifos Exposure [C] . Corie A. Ellison, James B. Knaak, Robin McDougall, ACS national meeting . 2012

机译：使用细胞色素P450特定参数和人类生物标志物数据开发针对皮毒死Expo暴露的人体生理学药代动力学/药效学模型
5. Generation of physiologically relevant kinetic data for the refinement of a human CYP-specific physiologically based Pharmacokinetic/Pharmacodynamic model to improve the risk assessment of two organophosphate pesticides; parathion and chlorpyrifos. [D] . Foxenberg, Robert John. 2007

机译：生成生理相关的动力学数据，以完善人类CYP特定的基于生理的药代动力学/药效学模型，以改善两种有机磷农药的风险评估；对硫磷和毒死rif。
6. Prediction of a Therapeutic Dose for Buagafuran a Potent Anxiolytic Agent by Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling Starting from Pharmacokinetics in Rats and Human [O] . Fen Yang, Baolian Wang, Zhihao Liu, 2017

机译：从大鼠和人体内的药代动力学出发通过基于生理学的药代动力学/药效学模型预测布加呋喃（一种有效的抗焦虑药）的治疗剂量
7. Prediction of Therapeutic Doses of Beta-Adrenergic Receptor Blocking Agents Based on Quantitative Structure-Pharmacokinetic/Pharmacodynamic Relationship. [O] . Yasuhiko YAMADA, Kiyomi ITO, Kouichi NAKAMURA, 1993

机译：基于定量结构 - 药代动力学/药效学相关的β-肾上腺素能受体阻断剂的治疗剂量预测。
8. A Physiologically-based Pharmacokinetic and Pharmacodynamic Model for the Oral Dosing of Rats with Ethyl Acrylate and Its Implications for Risk Assessment (paper Preprint) W-letter. [R] . 1992

机译：基于生理学的药代动力学和药效学模型，用于口服丙烯酸乙酯大鼠及其对风险评估的影响（纸质预印本）W字母。

Prediction of a Therapeutic Dose for Buagafuran, a Potent Anxiolytic Agent by Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling Starting from Pharmacokinetics in Rats and Human

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